Neonatology (Neonatal Intensive Care Unit)

Robin Heise Steinhorn, MD

• Head, Division of Neonatology
• Director Neonatal-Perinatal Medicine Fellowship
• Associate Chair for NMH, Department of Pediatrics
• Associate Professor of Pediatrics
• Attending Neonatologist, Children's Memorial Hospital
• Attending Neonatologist, Northwestern Memorial Hospital

Contact information

• The Children's Memorial Hospital 2300 Children's Plaza, #45 Chicago, IL 60614
• Phone: 773.880.4142
• Fax: 773.880.3061
• Email: r-steinhorn@northwestern.edu

Education

• BS, Biology, The University of Akron
• MD, Washington University, St. Louis

Graduate medical education

• Residency in Pediatrics, The University of Minnesota
• Fellowship in Neonatology, The University of Minnesota

Professional organizations

• Extracorporeal Life Support Organization
• American Academy of Pediatrics
• Society for Pediatric Research
• American Heart Association
• American Thoracic Association
• Perinatal Research Society

Honors and awards

• Lincoln Park Chamber of Commerce: 'Heart Of the Park Service Award'
• Today's Chicago Women: Named in '100 Women Making a Difference'
• AHA Established Investigator Award · Robert H. Bartlett Award
• Alpha Omega Alpha

Selected References

• Steinhorn RH, Isham-Schopf B, Smith C, Green TP: Hemolysis during long-term extracorporeal membrane oxygenation (ECMO). J Pediatr 115:625-630, 1989.
• Steinhorn RH, Green TP: The use of ECMO in the treatment of respiratory syncytial virus bronchiolitis: the national experience, 1983-1988. J Pediatr 116:338-342, 1990.
• Zach TL, Steinhorn RH, Georgieff MK, Mills MM, Green TP: Leukopenia and infectious complications in critically ill newborn infants: Effects of extracorporeal membrane oxygenation. J Pediatr 116:440-443, 1990.
• Green TP, Isham-Schopf B, Steinhorn RH, Smith C, Irmiter RJ: Whole blood activated clotting time in infants during extracorporeal membrane oxygenation. Crit Care Med 18:494-498, 1990.
• Green TP, Isham-Schopf B, Irmiter RJ, Smith C, Uden DL, Steinhorn RH: Extracorporeal inactivation of heparin during ECMO in infants. Clin Pharmacol Ther 48:148-154,1990.
• Steinhorn RH, Morin FC III, Gugino SF, Giese EC, Russell JA. Developmental differences in endothelium-dependent responses in isolated ovine pulmonary arteries and veins. Am J Physiol 264:H2162-H2167, 1993.
• Steinhorn RH, Morin FC III, Van Wylen DGL, Russell JA. Endothelium-dependent relaxations to adenosine in juvenile rabbit pulmonary arteries and veins. Am J Physiol 266: H2001-2006, 1994.
• Steinhorn RH, Kriesmer PJ, Green TP, McKay CJ, Payne NR. Congenital diaphragmatic hernia in Minnesota: Impact of antenatal diagnosis on survival. Arch Pediatr Adoles Med 148: 626-631, 1994.
• Karamanoukian H, Glick PL, Zayak M, Steinhorn RH, Fineman JR, Morin FC III. Effect of nitric oxide in infants with pulmonary hypoplasia before and after ECMO. Pediatrics 94: 715-718. 1994. · Steinhorn RH, Morin FC III, Russell JA. The adventitia may be a diffusion barrier specific to nitric oxide. J Clin Invest 94: 1883-1888, 1994.
• Steinhorn RH, Russell JA, Morin FC III. Disruption of cyclic GMP production in pulmonary arteries isolated from newborn lambs with pulmonary hypertension. Am J Physiol 268: H1483-H1489, 1995.

• Thusu KG, Morin FC III, Russell JA, Steinhorn RH. The specific cGMP phosphodiesterase inhibitor M&B 22948 enhances the effect of nitric oxide in newborn lambs with persistent pulmonary hypertension. Am J Resp Crit Care Med 152: 1605-1610, 1995. Driscoll W, Thurin SM, Carrion V, Steinhorn RH, Morin FC III. Effect of methylene blue on refractory neonatal hypotension. J Pediatr 129: 904-908, 1996.
• McDonald JV, Green TP, Steinhorn RH. The role of the centrifugal pump in hemolysis during neonatal extracorporeal support. ASAIO J 43: 35-38, 1997.
• Steinhorn RH, Cox PN, Fineman JR, Finer NN, Rosenberg EM, Silver MM, Zwass MC, Morin FC III. A response to inhaled nitric oxide does not predict survival in persistent pulmonary hypertension of the newborn due to alveolar capillary dysplasia. J Pediatr 130: 417-422, 1997.
• Shaul PW, Yuhanna IS, German Z, Chen Z, Steinhorn RH, Morin FC III. Pulmonary endothelial nitric oxide synthase gene expression is decreased in fetal lambs with pulmonary hypertension. Am J Physiol 272 (Lung Cell. Mol. Physiol 16): L1005-L1012, 1997.
• D'Angelis C, Steinhorn RH, Morin FC III, Nickerson PA. Localization of soluble guanylate cyclase in pulmonary vasculature of fetal sheep. Anatomical Record 250: 62-69, 1998. · Irish MS, Glick PL, Russell JA, Kapur P, Bambini DA, Holm BA, Steinhorn RH. Contractile properties of intralobar pulmonary arteries and veins in the fetal lamb model of congenital diaphragmatic hernia. J Pediatr Surg 33: 921-928, 1998.
• Dukarm RC, Russell JA, Morin FC III, Steinhorn RH. Pulmonary and systemic effects of the phosphodiesterase inhibitor dipyridamole in persistent pulmonary hypertension. Pediatr Res 44: 831-837, 1998.

• Black SM, Fineman JR, Steinhorn RH, Bristow J, Soifer S. Altered molecular expression of nitric oxide synthase in a lamb model of increased pulmonary blood flow. Am J Physiol 275: H1643-H1651, 1998.
• Millard SL, Russell JA, Morin FC III, Adolf M, Gugino S, Steinhorn RH. cGMP inhibition of endothelin-stimulated phosphoinositide turnover in the fetal lamb pulmonary artery ring. Pulm Pharmacol Ther 11: 201-204, 1998.
• Calvo WJ, Hajduczok G, Russell JA, Steinhorn RH, Diamond SL. Inhibition of nitric oxide but not prostacyclin prevents poststenotic dilatation in rabbit femoral artery. Circulation 99: 1069-1078, 1999.
• Dukarm RC, Russell JA, Morin FC III, Steinhorn RH. The phosphodiesterase inhibitor E4021 selectively dilates the pulmonary circulation. Am J Resp Crit Care Med: 858-65, 1999.
• Hintz SR, Vincent JA, Pitlick PT Steinhorn RH, Fineman JR, Kim GE, Benitz WE. Alveolar Capillary Dysplasia: Diagnostic potential for cardiac catheterization. J Perinatol 19: 441-446, 1999. · Lakshinrusimha S, Steinhorn RH. Pulmonary vascular adaptation at birth. In: Neonatal Resuscitation. Clin Perinatol 26:601-19, 1999.
• Steinhorn RH, Gordon JB, Tod ML. Effect of cGMP specific phosphodiesterase inhibition on inhaled nitric oxide in isolated lamb lungs. Crit Care Med 28: 490-495, 2000.
• Gunnarsson B, Heard CM, Rotta AT, Brecher, ML, Steinhorn RH. Successful lysis of an obstructive aortic thrombus in an infant on extracorporeal membrane oxygenation. J Perinatol, in press. · Tzao C, Nickerson PA, Russell JA, Nobel BK, Steinhorn RH. Heterogeneous distribution of type I nitric oxide synthase in pulmonary vasculature of ovine fetus. Histochem J, in press.
• Steinhorn RH, Russell, JA, Lakshminrusimha S, Gugino SF, Black SM, Fineman JR. Altered endothelium-dependent relaxation in lambs with high pulmonary blood flow and pulmonary hypertension. Am J Physiol, in press. Selected Book Chapters And Editorials
• Steinhorn RH, Glick PL, O'Toole SJ, Morin FC III. Contemporary management of the infant with congenital diaphragmatic hernia. In: Current Topics in Neonatology. WB Saunders, Philadelphia, PA. Chapter 11, pp 224-255, 1997. T Hanson, editor.

• Steinhorn RH, Millard SL, Morin FC III. Persistent pulmonary hypertension of the newborn: Role of lipid mediators, endothelin, and nitric oxide in pathophysiology and treatment. Clin Perinatol 22: 405-428, 1995. WB Saunders, Philadelphia, PA. M Caplan, J Hageman, editors.
• Dukarm RC, Steinhorn RH, Morin FC III. The normal cardiopulmonary transition at birth. In: Congenital Diaphragmatic Hernia. Clin Perinatol 23: 711-726, 1996. WB Saunders, Philadelphia, PA. P Glick, M Irish, B Holm, editors.
• Steinhorn RH. Antenatal Ultrasonography: First Do No Harm? Lancet 352: 1568-1569, 1998.
• Steinhorn RH. Persistent Pulmonary Hypertension of the Newborn. Acta Anaesth Scandinavica. 41 (Supplement III): 135-140, 1997.
• Steinhorn RH. Advances in the management of respiratory failure: Nitric oxide. ASAIO J 42: 99-100, 1996.
• Steinhorn RH, Morin FC III, Fineman JR. Models of persistent pulmonary hypertension and the role of cGMP in pulmonary vasorelaxation. Seminar Perinatol 21: 393-408, 1997.
• Steinhorn RH, Fineman JR. The pathophysiology of pulmonary hypertension in congenital heart disease. Artificial Organs 23: 970-974, 1999.
• Steinhorn RH, Russell JA. Nitric Oxide and Persistent Pulmonary Hypertension. In: Nitric Oxide Biology and Pathobiology. Academic Press, San Diego CA. Chapter 58, pp 963-981. Louis Ignarro, editor.